MOTS-c

MOTS-c is a fascinating peptide that has been gaining popularity for its potential benefits for metabolism, aging, and overall health. Here's what we know so far:

*What is MOTS-c?*

MOTS-c is a 16-amino-acid peptide encoded by the mitochondrial 12S rRNA gene. It is produced in response to stress or exercise and plays a role in regulating glucose metabolism, insulin sensitivity, and inflammation.

*Benefits:*

- *Improved Insulin Sensitivity*: MOTS-c improves glucose uptake in skeletal muscle, reducing insulin resistance and improving glucose metabolism.

- *Weight Loss*: Studies show that MOTS-c treatment leads to weight loss and a reduction in adiposity.

- *Anti-inflammatory Effects*: MOTS-c reduces pro-inflammatory cytokines and increases anti-inflammatory factors.

* - *Neuroprotection*: MOTS-c may have protective effects on the brain and nervous system. - *Cardioprotection*: MOTS-c improves cardiovascular function and reduces vascular calcification.

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*Mechanism of action:*

- MOTS-c activates the AMPK pathway, regulating energy metabolism and insulin sensitivity.

- It also inhibits the MAPK-c-Fos pathway, reducing inflammation and pain.²³

*Potential applications:*

- *Type 2 diabetes*: MOTS-c may help regulate blood sugar levels and improve insulin sensitivity.

- *Obesity*: MOTS-c may help with weight loss and reduce adiposity.

- *Aging*: The anti-inflammatory and antioxidant effects of MOTS-c may contribute to healthy aging.

Research-grade ultrapure peptide: minimum purity of 98%

Supplied in sterile, flip-top vials with headspace, designed for laboratory use.

Manufactured to rigorous standards and trusted by researchers worldwide.

All our peptides are supplied exclusively for research and laboratory use. Each vial contains sterile, lyophilized powder, finely ground and sieved to ensure consistency. The stated weight refers to the contents of a single vial. Reconstitution requires bacteriostatic water with 0.9% benzyl alcohol (or a suitable equivalent). Please note that we do not provide advice or recommendations regarding dosage, administration, or use in humans or animals.

Chemical Information:

Synonyms: MOTS-C, Mitochondrial-derived peptide

Molecular formula: C₉₀H₁₄₀N₂₈O₂₀S₂

Molecular weight: Approximately 2002.4 Da

Sequence: Met-Arg-Trp-Gln-Glu-Met-Gly-Tyr-Ile-Phe-Tyr-Pro-Arg-Lys-Leu-Arg