MOTS-c

MOTS-c is a fascinating peptide that's been gaining attention for its potential benefits on metabolism, aging, and overall health. Here's what we know so far:

*What is MOTS-c?*

MOTS-c is a 16-amino acid peptide encoded by the mitochondrial 12S rRNA gene. It's produced in response to stress or exercise and plays a role in regulating glucose metabolism, insulin sensitivity, and inflammation.

*Benefits:*

- *Improved Insulin Sensitivity*: MOTS-c enhances glucose uptake in skeletal muscle, reducing insulin resistance and improving glucose metabolism.

- *Weight Loss*: Studies show MOTS-c treatment leads to weight loss and reduced adiposity.

- *Anti-Inflammatory Effects*: MOTS-c reduces pro-inflammatory cytokines and increases anti-inflammatory factors.

- *Neuroprotection*: MOTS-c may have protective effects on the brain and nervous system.

- *Cardio Protection*: MOTS-c improves cardiovascular function and reduces vascular calcification.

*Mechanism of Action:*

- MOTS-c activates the AMPK pathway, regulating energy metabolism and insulin sensitivity.

- It also inhibits the MAPK-c-Fos pathway, reducing inflammation and pain ² ³.

*Potential Applications:*

- *Type 2 Diabetes*: MOTS-c may help regulate blood sugar levels and improve insulin sensitivity.

- *Obesity*: MOTS-c could aid in weight loss and reduce adiposity.

- *Aging*: MOTS-c's anti-inflammatory and antioxidant effects may contribute to healthy aging.

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• Ultra-Pure Research Grade Peptide – Minimum 98% Purity

• Supplied in sterile, flip-top headspace vials designed for laboratory use

• Manufactured to exacting standards and trusted by researchers worldwide

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All of our peptides are supplied strictly for research and laboratory use only. Each vial contains sterile, lyophilised powder that has been finely milled and sieved to ensure consistency. The stated weight refers to the content of a single vial. Reconstitution requires Bacteriostatic Water containing 0.9% Benzyl Alcohol (or a suitable equivalent). Please note that we do not offer any advice or recommendations regarding dosage, administration, or use in humans or animals.

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Chemical Information:

• Synonyms: MOTS-C, Mitochondrial Derived Peptide

• CAS Number: n/a

• Molecular Formula: C₉₀H₁₄₀N₂₈O₂₀S₂

• Molecular Weight: Approximately 2002.4 Da 

• Sequence: Met-Arg-Trp-Gln-Glu-Met-Gly-Tyr-Ile-Phe-Tyr-Pro-Arg-Lys-Leu-Arg

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